Steroids Def Of Medical Terms
A chronic, relapsing disease, characterized by compulsive drug-seeking and use
and by neurochemical and molecular changes in the brain.
Anabolism – constructive metabolism characterized by the building of tissue
into more complex living matter, mainly muscle.
Anabolic – promoting anabolism
Anabolic steroid – any one of several compounds derived from testosterone or
prepared synthetically to promote general body growth, to oppose the effects of
endogenous estrogen, or to promote masculinization effects. They have a
chemical structure similar to cholesterol.
effects – Drug-induced growth or thickening of the body’s nonreproductive tract
tissuesÑincluding skeletal muscle, bones, the larynx, and vocal cords and
decrease in body fat.
Analgesics – A group of medications that reduce pain.
Androgen – any steroid hormone that promotes male characteristics.
Androgenic effects – A drug’s effects upon the growth of the male reproductive
tract and the development of male secondary sexual characteristics.
Antidepressants – A group of drugs used in treating depressive disorders
Aromatize – the on take of feminine characteristics or feminization.
Atrophy – refers to a state of deterioration usually within the muscle or
bodily organ due to a lack of use or health.
ATP – adenosine triphosphate is a molecule used to store and release energy in
Bitch Tits – a slang term for gynecomastia.
Blending – Mixing different drugs.
Bulking up – Increasing muscle mass through steroids.
Cardiovascular system – The heart and blood vessels.
Catabolism – a complex metabolic process in which energy is liberated for use
in work, energy storage, or heat production by the destruction of complex
substances. Basically muscle tissue is broken down when a person is in a
catabolic state and the use of anabolic steroids will change this.
Cholesterol – a fatty substance found in animals that performs many vital
functions and is synthesized by the liver and the adrenal cortex.
Creatine – a nitrogenous compound that when combined with phosphate produces
Cycle – the time in which a certain supplement is taken. If you take a
supplement for 6 weeks it is a 6-week cycle. Usually the time on a cycle is
followed by the same amount of time off of the cycle.
Cycling – Taking multiple doses of steroids over a specified period of time,
stopping for a time and starting again.
Dart, poke, pin, ned – slang terms for syringes.
Diuretic – a substance that increases the amount of urine which is released by
Doping – Using drugs and other nonfood substances to improve athletic
performance and prowess.
Ergogenic drugs – Performance enhancing substances.
Estrogen – natural hormone that promotes the growth and development of female
Fakes or basement drug – refers to counterfeit or fake steroids.
Freaky – A bodybuilding term used to describe a person who is huge and
obviously on steroids.
Gear – slang for steroids, syringes, anything associated with the use of
Gynecomastia – an abnormal enlargement of one or both breasts in men. This
condition is usually temporary due to a hormonal imbalance brought on by the
use of steroids, however, can occur naturally as well.
Hormone – A chemical substance formed in glands in the body and carried in the
blood to organs and tissues, where it influences function, structure, and
Immune system – the system in a persons body that wards off infection and
responds to illness.
Juice – slang term for injectable steroids
Lean mass – the amount of muscle on a persons body
Libido – a persons sex drive.
Megadosing – Taking massive amounts of steroids, by injection or pill.
Musculoskeletal system – The muscles, bones, tendons, and ligaments.
Placebo – An inactive substance, used in experiments to distinguish between
actual drug effects and effects that are expected by the volunteers in the
Plateauing – When a drug becomes ineffective at a certain level.
Roid rages – Uncontrolled outbursts of anger, frustration or combativeness that
may result from using anabolic steroids.
Sex hormones – Hormones that are found in higher quantities in one sex than in
the other. Male sex hormones are the androgens, which include testosterone; and
the female sex hormones are the estrogens and progesterone.
Shotgunning – Taking steroids on a hit-or-miss basis.
Stacking – Using a combination of anabolic steroids, often in combination with
Steroid – any of a large number of hormonal substances with the same basic
chemical structure produced mainly in the adrenal cortex and gonads.
Tapering – Slowly decreasing steroids intake.
Trade name – the name given to a particular substance by each company that
Testosterone – an androgenic hormone which is used to produce anabolic
Thermogenesis – the production of heat. Raises metabolism making it easier to
Virilization – the process in which a person takes on the characteristics of a
mature male. Masculinization.
Withdrawal – Symptoms that occur after chronic use of a drug is reduced or
AR – androgen receptor.
ABSCESS – an abscess forms when pus accumulates in a localized area of the
body. An abscess is caused by infection from bacteria, viruses, parasites, and
fungi. The infection becomes swollen, tender and inflamed and there may be
associated fever and chills. An abscess can be the result of an injury, and it
can be internal or external. Some abscesses are removed through surgery.
ADIPOSE TISSUE – fat.
ADRENAL GLANDS – a pair of hormone-producing organs located near the kidneys.
ADRENALIN – A trade name for the hormone epinephrine.
ADRENOCEPTOR – a receptor that responds to hormones (such as epinephrine
(adrenaline)) produced by the adrenal gland.
AGONIST – a chemical agent that stimulates, activates, accelerates, or enhances
a process in the body.
ANABOLIC, ANABOLISM – tending to build or repair tissue, muscle tissue in
ANABOLIC STEROID – a synthetic steroid used to increase muscle mass and weight.
Anabolic steroids are versions of the natural hormone testosterone but have
fewer masculinizing effects. Anabolic steroids have been used to reverse
AIDS-related wasting syndrome on an individual basis, but trial data are
ANDROGEN – a masculinizing hormone such as testosterone.
ANDROGENIC – producing or accentuating male sexual characteristics (body hair,
deepened voice, male pattern baldness). One of the characteristics of steroids,
whether synthesized in the lab or naturally in the body is their
anabolic-androgenic ratio: if some amount of steroid X produces the same
anabolic effects as a given amount of testosterone, how do the androgenic
effects compare to those produced by that quantity of testosterone.
ANTIANDROGEN – a drug used to interfere with the action of male sex hormones.
In hormone thereapy, it is usually a synthetic drug such as Casodex, flutamide,
cyproterone and nilutamide; a hormone antagonist.
ANTI-E’s, ANTI-ESTROGENS – “aromatase inhibitors” bind to the same site on the
enzyme aromatase as testosterone does. This allows less testosterone to bind to
aromatase, which in turn means less is converted to oestradiol (the primary
type of oestrogen). An important point to note is that the amount of inhibitor
required rises with increasing steroid dose i.e. higher doses of Arimidex or
Proviron are required to prevent the aromatisation of 1000mg/week of
testosterone than 500mgs/week.
ANTAGONIST – counteracting or opposing. An antiandrogen would be an antagonist
because it blocks the action of androgens. Compare to agonist.
ANTIBIOTIC – a substance, especially one similar to those produced by certain
fungi for destroying bacteria, that kills or inhibits the growth of
microorganisms. An antibiotic is used to combat disease and infection.
AROMATASE – an enzyme responsible for (among other things) converting
testosterone into estrogens.
ATROPHY – refers to a state of deterioration usually within the muscle or
bodily organ due to a lack of use or health.
BIOAVAILABILITY – the extent to which an oral medication is absorbed in the
digestive tract and reaches the bloodstream.
BITCH TITS – a slang term for gynocomastia.
CNS – central nervous system.
CATABOLIC, CATABOLISM – tending to break down tissue, muscle tissue in
CORTICOSTEROID – any steroid substance obtained from the cortex or outer
portion of the adrenal gland or any synthetic substitute for such a steroid.
Corticosteriods are immunosuppressive and include prednisone, corticosterone,
cortisone and aldosterone.
CUTANEOUS – relating to the skin.
CUTTING, CUTTING UP – to lose bodyfat, preferably with as little loss of muscle
and other lean tissue as possible.
CYCLING – In reference to drugs or supplements, a “cycle” is a dosage
or usage regimen that lasts a finite period of time with a planned sequence of
doses and times, which may or may not be the same.
DHT, DIHYDROTESTOSTERONE – a highly androgenic hormone produced from
testosterone by the enzyme 5-alpha-reductase. This hormone is the primary
culprit in male pattern baldness and benign prostate enlargement.
DMSO, DIMETHYLSULFOXIDE – a transdermal carrier. Transdermal delivery allows
chemicals that would be broken down by the digestive system or destroyed by the
liver to pass into the bloodstream.
DNA – Acronym for deoxyribonucleic acid. The molecules inside cells that carry
genetic information and pass it from one generation to the next.
DIURETIC – a drug that increases the rate at which water is excreted through
DOUBLE-BLIND – a kind of clinical study in which neither the participants nor
the doctors know who is receiving the experimental drug and who is receiving
the placebo or standard comparison treatments. This method is believed to
achieve the most accuracy because neither the doctors nor the patients can
affect the observed results with their psychological biases.
DOWNREGULATION – Decreasing the activity or responsiveness of a physiological
process by reducing the number of available receptors.
ECA – Ephedrine, Caffeine, and Aspirin, a popular and effective thermogenic
combination of drugs used for weight loss and energy. Ephedrine is a stimulant
that acts to increase alertness, energy, and body temperature, thus increasing
caloric expenditure. Caffeine inhibits the body’s natural tendency to
counteract the stimulant effects of ephedrine, so that the two of them used
together increase caloric expenditures more than the sum of the increases caused
by each one used individually. The most common dosage is 200mg of caffeine
taken with 20mg of ephedrine ( = 25mg of ephedrine hydrochloride) three times
per day, the third dose being taken not later than dinnertime. Caffeine and
ephedrine act as appetite suppressants, which has weight-loss benefits as well.
60mg of aspirin (about a quarter of a standard aspirin tablet) is often added
to the stack, but studies have not shown conclusively that ECA is more
effective for weight loss than ephedrine and caffeine without aspirin. Please
note that ephedrine and caffeine also have a diuretic effect, so some weight
loss will be due to a loss of water and not fat.
ECTOMORPH – thin and linear body type
EDEMA – swelling caused by an abnormal accumulation of fluid in body tissues.
ENDOCRINE – The activity of a hormone or growth factors that circulates in
blood, and binds to and affects cells distant from the source of secretion.
ENDOCRINE GLAND – one of the organs in the body that produces hormones.
ENDOCRINE SYSTEM – your endocrine system is a system of glands. Glands are
organs that make hormones. These are substances that help to control activities
in your body. Hormones control reproduction, metabolism (food burning and waste
elimination), and growth and development. Hormones also control the way you
respond to your surroundings. They help to provide the proper amount of energy
and nutrition. The endocrine glands include the thyroid, parathyroid, pancreas,
ovaries, testes, adrenal, pituitary and hypothalamus.
ENDOMORPH – rounded body type with small shoulders.
ERGOGENIC – tending to increase muscular power, endurance, or size
ESTER – the length of time a drug’s molecules are released into your system.
ESTRADIOL – the hormone that promotes sexual maturity in females, is a key
hormone in the regulation of reproductive cycles, and maintains the
reproductive system capable of release of oocytes for fertilization. In
viviparous species, estrogen stimulates growth of reproductive organs during
ESTROGEN, ESTROGENIC – natural hormone that promotes the growth and development
of female characteristics. There is no one hormone named “estrogen”;
estrogens are hormones that induce or accentuate female sexual characteristics
(as well as performing other functions, depending on the specific hormone).
Estrogens include estrone, progesterone, and estradiol. “Estrogenic”
means “tending to induce the same effects that estrogen does”; while
chemicals that mimic testosterone are almost nonexistent in nature, our food
supply, and our environment, estrogenic chemicals are common. Also called
FDA – the Food and Drug Administration, an agency of the United States
Department of Health and Human Services that regulates the testing of
experimental drugs and approves new medical products for marketing based on
evidence of safety and efficacy
GEAR – slang for steroids, syringes, anything associated with the use of
FSH, FOLLICLE STIMULATING HORMONE – Follicle stimulating hormone prompts the
secretion of estradiol from ovarian follicles, from the granulosa cells. In
males, it stimulates the Sertoli cells to produce sperm.
FLAMING – when a post is written in a mean and negative tone having little
GONADOTROPIN – A term used to describe luteinizing and follicle-stimulating
hormones, hormones secreted from the anterior pituitary gland that control
several aspects of reproductive function.
GROWTH FACTOR – one of many intercellular regulatory molecules that affect cell
proliferation (rapid and repeated reproduction) and maturation in specific
GYNECOMASTIA – an abnormal enlargement of one or both breasts in men. This
condition is usually temporary due to a hormonal imbalance brought on by the
use of steroids, however, can occur naturally as well.
HGH, HUMAN GROWTH HORMONE – a peptide hormone secreted by the anterior
pituitary gland in the brain. HGH enhances tissue growth by stimulating protein
formation. A protein hormone secreted from the anterior pituitary that has
potent metabolic and growth-promoting activities. General anabolic stimulant,
increases release of insulin-like growth factor-I (IGF-I), cell growth and bone
HPA, HYPOTHALAMIC PITUITARY AXIS – Located in the hypothalamus are several
collections of cells that make hormones that stimulate other collections of
cells in the pituitary to produce and release hormones. A special network of
blood vessels connects the hypothalamus and pituitary making the
hypothalamic-pituitary axis functional.
HPTA, HYPOTHALAMIC PITUITARY TESTICULAR AXIS – homeostatic balance of
HALF-LIFE – the amount of time required for half of a given substance (such as
a drug) or half the current population of a given cell type to be eliminated
from the body.
HORMONE – an active chemical substance formed in one part of the body and
carried in the blood to other parts of the body where it stimulates or
suppresses cell and tissue activity.
HOMEOSTASIS – ways in which organisms try to keep conditions inside their body
as stable as possible. Whenever a physiological factor changes, the body
detects the change and then, by using nervous or hormonal signals (or both), it
reverses the change. The extent of the correction is monitored by a system
called negative feedback. This make sure that, as levels return to normal, the
corrective mechanisms are scaled down.
HOT FLASH – the sudden sensation of warmth in the face, neck and upper body; a
side effect of many forms of hormone therapy.
HYPERTENSION – high blood pressure.
HYPERTROPHY – an increase in size of cells (rather than number of cells); often
associated with an increase in organ size.
INFLAMMATION – the body’s response to tissue injury or infection which occurs
in the affected tissues and adjacent blood vessels. The blood vessels’
permeability is increased, and the area becomes heavily populated with white
blood cells. Signs of inflammation are redness, swelling, pain and sometimes
loss of function. Not all of these signs are necessarily present in any given
INSULIN – a hormone that promotes the uptake of nutrients (most notably
IGF-1, INSULIN-LIKE GROWTH FACTORS: polypeptide hormones synthesized by many
tissues. Insulin-like growth factor-1 synthesis is stimulated by growth
IM, INTRAMUSCULAR – injected directly into a muscle.
IV, INTRAVENOUS – injected directly into a vein.
JUICE – slang term for injectable steroids
LH, LUTEINIZING HORMONE – human chorionic gonadotropin (HCG) is similar and
produced in placenta.
LESION – a disturbed area of tissue -a wound, injury, nodule or tumor on the
skin or elsewhere.
LFT, LIVER FUNCTION TEST – a test that measures the blood serum level of any of
several enzymes produced by the liver. An elevated liver function test is a
sign of possible liver damage.
MCG, MICROGRAM: equal to 1,000 milligrams (mg).
MAINTENANCE THERAPY – extended drug therapy, usually at a diminished dose,
administered after a disease has been brought under control. Maintenance
therapy is utilized when a complete cure is not possible, and a disease is
likely to recur if therapy is halted.
MESOMOPRH – body type with thick muscles and heavy bone structure.
NSAID, NON-STEROIDAL ANTI-INFLAMMATORY – an anti-inflammatory agent or drug
that is not a steroid; these include aspirin, ibuprofen, naprosyn, and
ketoprofen, but not acetaminophen.
NEGATIVE FEEDBACK – a mechanism commonly used for control of secretion in the
OESTROGEN – see Estrogen.
OFF-LABEL – use of a drug for a disease or condition other than the indication
for which it was approved by the FDA. For example, many doctors prescribe
paromomycin (humatin) for cryptosporidiosis, although it is not approved for
treating this disease.
PARENTERAL – taken by needle.
PLOGEL, PLOJEL – a transdermal carrier. Transdermal delivery allows chemicals
that would be broken down by the digestive system or destroyed by the liver to
pass into the bloodstream.
PRE-CLINICAL – refers to the testing of experimental drug the test tube or in
animals-the testing that occurs be trials in humans may be carried out.
PROGESTERONE – a female hormone.
PROHORMONE – prohormones are actually hormones themselves and are chemicals
produced by the body (or close “chemical cousins” of such chemicals,
as is the case with the nor- varieties). The “pro-” part is used for
two reasons: first, because rather than themselves being the hormone one is
actually interested in supplementing, they are instead used by the body’s
biochemical pathways to produce the hormone of interest; second, marketing.
PROLACTIN – prolactin is a hormone produced in the pituitary that stimulates
the mammary glands to produce milk. Prolactin has other functions including an
essential role in the maintenance of immune system functions. Prolactin levels
rise during the latter part of pregnancy but the effects on lactation are
suppressed by high levels of progesterone. Once progesterone drops at
childbirth, milk secretion begins.
PROSTATE – the prostate gland is about the size and shape of a walnut. This
gland produces a milky fluid (seminal fluid) that helps to protect and
transport sperm and ensure fertility. It also helps to control the flow of
urine. The gland wraps around your urethra, the tube through which urine
RECEPTOR – a chemical site either within the cell or on the surface of the cell
membrane that responds to the presence of a chemical stimulus such as a hormone
or neurotransmitter and triggers a series of chemical events that produce a
response on a cellular level.
RENAL – of or relating to the kidneys.
RIPPED – visibility of fine detail below the level of individual muscles and
muscle heads. To be “ripped,” it should be easy to identify by sight
the striations and muscle bands going across the heads of the deltoid, and the
different heads of the quadriceps.
STEROID – a member of a large family of structurally similar lipid substances.
Steroid molecules have a basic skeleton consisting of four interconnected
carbon rings. Different classes of steroids have different functions. All the
sex hormones are steroids. Anabolic steroids increase muscle mass.
Anti-inflammatory steroids (or corticosteroids) can reduce swelling, pain and
other manifestations of inflammation.
SLIN – slang for insulin.
STACKING – Using a combination of anabolic steroids, often in combination with
SUBCUTANEOUS – beneath the skin.
SUBLINGUAL – absorbed into the bloodstream through the skin under the tongue,
an area with especially thin skin and a rich blood supply. Bypasses the liver
and the rest of the digestive system and exposure to all the acids and enzymes
TAPERING OFF – reducing quantities taken of a drug or supplement at the end of
TESTOSTERONE – the primary natural androgenic and anabolic steroid hormone
found in the body – a naturally occurring male hormone. When administered as a
drug it can cause gain in lean body mass, increased sex drive and possibly
aggressive behavior. Many men with HIV have low testosterone levels.
TRH, THYROTROPIN RELEASING HORMONE – A molecule produced by the hypothalamus
that stimulates the pituitary gland to release thyroid stimulating hormone that
in turn stimulates the release of thyroid hormone from the thyroid gland.
TSH, THYROTROPIN – thyroid-stimulating hormone;
TOPICAL – applied directly to the skin.
TOXICITY – the harmful effects of a given drug that occur during therapy. The
term is similar to side effect and adverse reaction.
TRANSDERMAL – through the skin; as in transdermally-delivered drugs such as
testosterone and estrogen patches. Transdermal delivery allows chemicals that
would be broken down by the digestive system or destroyed by the liver to pass
into the bloodstream. It also can provide a slow and steady level of the
chemical rather than a sudden “pulse” when hitting the digestive
TRIBULUS TERRESTERIS – herb or herbal extract supplying protodioscin, which has
been shown to increase erectile response in rabbits. It has not, however, been
shown to increase total or free testosterone levels and studies on strength and
body composition on resistance-trained males have shown reduced gains in the
tribulus group compared with the placebo group.
UPREGULATION – Increasing the activity or responsiveness of a physiological
process by increasing the number of available receptors.
VIRILIZATION – the process in which a person takes on the characteristics of a
mature male; masculinization.